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MORC2 Polyklonaler Antikörper

MORC2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23202-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using MORC2 Polyclonal antibody (23202-1-AP)

    WB analysis using 23202-1-AP (same clone as 23202-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23202-1-AP (MORC2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23202-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

23202-1-PBS bindet in WB, Indirect ELISA MORC2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MORC2 fusion protein Ag19605
Vollständiger Name MORC family CW-type zinc finger 2
Berechnetes Molekulargewicht 970 aa, 111 kDa
Beobachtetes Molekulargewicht118 kDa
GenBank-ZugangsnummerBC136782
Gene symbol MORC2
Gene ID (NCBI) 22880
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MORC2 is essential for epigenetic silencing by the HUSH (human silencing hub) complex. It can be recruited by HUSH to target site in heterochromatin. MORC2 also recruits histone deacetylases, such as HDAC4, to promoter regions, causing local histone H3 deacetylation and transcriptional repression of genes.