MOV10 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

MOV10 Polyklonal Antikörper für WB, IHC, IF/ICC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10370-1-PBS

Synonyme

Armitage homolog, EC:3.6.4.13, fSAP113, gb110, Helicase MOV-10

---

• 

  WB analysis using 10370-1-AP (same clone as 10370-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 10370-1-AP (MOV10 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HepG2 using 10370-1-AP (same clone as 10370-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 10370-1-AP (MOV10 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human liver using 10370-1-AP (same clone as 10370-1-PBS)

  human liver tissue were subjected to SDS PAGE followed by western blot with 10370-1-AP (MOV10 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

• 

  IP experiment of HepG2 using 10370-1-AP (same clone as 10370-1-PBS)

  IP result of anti-MOV10 (IP:10370-1-AP, 4ug; Detection:10370-1-AP 1:5000) with HepG2 cells lysate 1480 ug. This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate hyperplasia using 10370-1-AP (same clone as 10370-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate hyperplasia tissue slide using 10370-1-AP (MOV10 antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate hyperplasia using 10370-1-AP (same clone as 10370-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate hyperplasia tissue slide using 10370-1-AP (MOV10 antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HepG2 using 10370-1-AP (same clone as 10370-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using MOV10 antibody (10370-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

• 

  IF Staining of MCF-7 using 10370-1-AP (same clone as 10370-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using MOV10 antibody (10370-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 10370-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

10370-1-PBS bindet in WB, IHC, IF/ICC, IP, Indirect ELISA MOV10 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: MOV10 fusion protein Ag0384
• Vollständiger Name: Mov10, Moloney leukemia virus 10, homolog (mouse)
• Berechnetes Molekulargewicht: 114 kDa
• Beobachtetes Molekulargewicht: 110-115 kDa
• GenBank-Zugangsnummer: BC002548
• Gene symbol: MOV10
• Gene ID (NCBI): 4343
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MOV10, also named as KIAA1631, belongs to the DNA2/NAM7 helicase family and SDE3 subfamily. It is required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Human MOV10 may regulate a wide range of RNA viruses and could also control the retrotransposition of endogenous retroelements in mammals(PMID:22727223). MOV10 has a broad antiretroviral activity that can target a wide range of retroviruses, and it could be actively involved in host defense against retroviral infection. MOV10 can potently inhibit HIV-1 replication at multiple stages(PMID:20215113). It is involved in the progression of telomerase-catalyzing reaction via the interaction of telomerase protein and telomere DNA.

{{ptg:RelatedPrimaryAntibodies}}