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MOV10 Rekombinanter Antikörper

MOV10 Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250130D2

Kat-Nr. : 85818-5-PBS

Synonyme

Armitage homolog, EC:3.6.4.13, fSAP113, gb110, Helicase MOV-10

Filter:
  • Western Blot (WB) analysis of various lysates using MOV10 Recombinant antibody (85818-5-RR)

    WB analysis using 85818-5-RR (same clone as 85818-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85818-5-RR (MOV10 antibody) at dilution of 1:30000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85818-5-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using MOV10 Recombinant antibody (85818-5-RR)

    IF Staining of HepG2 using 85818-5-RR (same clone as 85818-5-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using MOV10 antibody (85818-5-RR, Clone: 250130D2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 85818-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85818-5-RR

    Affinity and Kinetic Characterization of 85818-5-RR

    Biolayer interferometry (BLl) kinetic assays of 85818-5-RR against Human MOV10 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

85818-5-PBS bindet in WB, IF/ICC, Indirect ELISA MOV10 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen MOV10 fusion protein Ag0384
Vollständiger Name Mov10, Moloney leukemia virus 10, homolog (mouse)
Berechnetes Molekulargewicht 114 kDa
Beobachtetes Molekulargewicht 115 kDa
GenBank-ZugangsnummerBC002548
Gene symbol MOV10
Gene ID (NCBI) 4343
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MOV10, also named as KIAA1631, belongs to the DNA2/NAM7 helicase family and SDE3 subfamily. It is required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Human MOV10 may regulate a wide range of RNA viruses and could also control the retrotransposition of endogenous retroelements in mammals (PMID:22727223). MOV10 has a broad antiretroviral activity that can target a wide range of retroviruses, and it could be actively involved in host defense against retroviral infection. MOV10 can potently inhibit HIV-1 replication at multiple stages (PMID:20215113). It is involved in the progression of telomerase-catalyzing reaction via the interaction of telomerase protein and telomere DNA.