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MS4A2 Polyklonaler Antikörper

MS4A2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26808-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using MS4A2 Polyclonal antibody (26808-1-AP)

    WB analysis using 26808-1-AP (same clone as 26808-1-PBS)

    mouse lung tissue lysates were subjected to SDS PAGE followed by western blot with 26808-1-AP (MS4A2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26808-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

26808-1-PBS bindet in WB, Indirect ELISA MS4A2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MS4A2 fusion protein Ag25196
Vollständiger Name membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
Berechnetes Molekulargewicht 244 aa, 27 kDa
Beobachtetes Molekulargewicht 25-27 kDa
GenBank-ZugangsnummerBC074843
Gene symbol MS4A2
Gene ID (NCBI) 2206
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MS4A is a new gene family with four transmembrane-spanning domains and is crucial for cell differentiation, signaling, and cell cycle control. The membrane-spanning 4 domains, superfamily A, number 2 gene (MS4A2, also named as the beta-chain of the high affinity IgE receptor or FcεRIβ gene, FCER1B), as a member of the MS4A family, is a component of the high-affinity IgE receptor, with co-immunoprecipitation experiments demonstrating that it associates with FcɛRIα and FcRγ to form a tetrameric receptor complex (αβγ2) that is expressed on mast cells and basophils at high density(PMID: 25835430). MS4A2 is strongly associated with the prognosis of lung adenocarcinoma and lung cancer brain metastases(PMID: 37533433).