MS4A7 Polyklonaler Antikörper
MS4A7 Polyklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 11864-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
11864-1-PBS bindet in WB, Indirect ELISA MS4A7 und zeigt Reaktivität mit human, Maus
| Getestete Reaktivität | human, Maus |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | MS4A7 fusion protein Ag2442 |
| Vollständiger Name | membrane-spanning 4-domains, subfamily A, member 7 |
| Berechnetes Molekulargewicht | 240 aa, 26 kDa |
| Beobachtetes Molekulargewicht | 26 kDa |
| GenBank-Zugangsnummer | BC020673 |
| Gene symbol | MS4A7 |
| Gene ID (NCBI) | 58475 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
The human MS4A family currently includes 18 members, and these proteins have four putative transmembrane domains (tetraspan) and several protein kinase C (PKC) phosphorylation sites. Membrane-spanning 4-domains a7 (MS4A7) is a member of the MS4A family. It is expressed by myeloid cells. MS4A7 can act as a NAM-specific pathogenic factor that exacerbates metabolic dysfunction-associated steatohepatitis (MASH) progression in mice (PMID: 38478630). There are two isoforms of MS4A7 protein, with molecular weights of 26.14 kDa and 21.41 kDa respectively.

