MSL2 Polyklonaler Antikörper

MSL2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23601-1-PBS

Synonyme

RNF184, MSL2L1, MSL2 like 1, MSL 2, MS L2

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  WB analysis using 23601-1-AP (same clone as 23601-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 23601-1-AP (MSL2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23601-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

23601-1-PBS bindet in WB, Indirect ELISA MSL2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: MSL2 fusion protein Ag18727
• Vollständiger Name: male-specific lethal 2 homolog (Drosophila)
• Berechnetes Molekulargewicht: 577 aa, 63 kDa
• Beobachtetes Molekulargewicht: 70-75 kDa
• GenBank-Zugangsnummer: BC093790
• Gene symbol: MSL2
• Gene ID (NCBI): 55167
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-affinitätsgereinigt
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

In mammals, MSL2 participates in histone H2B ubiquitination (H2Bub1) via the MSL complex, regulating transcription and chromatin remodeling. It is essential for embryonic development and has been implicated in cancer progression. MSL2's dysfunction is linked to developmental defects and oncogenesis, highlighting its critical role in gene regulation. (PMID: 30669413; PMID: 34899909)