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MSRA Rekombinanter Antikörper

MSRA Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251025H2

Kat-Nr. : 86358-1-PBS

Synonyme

EC:1.8.4.11, Mitochondrial peptide methionine sulfoxide reductase, Peptide Met(O) reductase, Peptide-methionine, PMSR

Filter:
  • Western Blot (WB) analysis of various lysates using MSRA Recombinant antibody (86358-1-RR)

    WB analysis using 86358-1-RR (same clone as 86358-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86358-1-RR (MSRA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86358-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of THP-1 cells using MSRA Recombinant antibody (86358-1-RR)

    IF Staining of THP-1 using 86358-1-RR (same clone as 86358-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using MSRA antibody (86358-1-RR, Clone: 251025H2 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 86358-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86358-1-PBS bindet in WB, IF/ICC, Indirect ELISA MSRA und zeigt Reaktivität mit human, Ratten

Getestete Reaktivität human, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen MSRA fusion protein Ag6053
Vollständiger Name methionine sulfoxide reductase A
Berechnetes Molekulargewicht 26 kDa
Beobachtetes Molekulargewicht 24-26 kDa
GenBank-ZugangsnummerBC054033
Gene symbol MSRA
Gene ID (NCBI) 4482
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Methionine sulfoxide reductase A (MSRA) is an antioxidant enzyme found in all domains of life that catalyzes the reduction of methionine-S-sulfoxide (MSO) to methionine in proteins and free amino acids (PMID: 28874471). MSRA has some isoforms with MW of 19~26 kDa. MSRA functions in the repair of oxidatively damaged proteins to restore biological activity. Transfection of MSRA reduced colony formation and the invasiveness of HCC cell lines. Studies have demonstrated the downregulation of MSRA in multiple human tumors, including breast cancers and its levels have been linked to advanced tumor grades (PMID: 20937881).