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MTERF4 Polyklonaler Antikörper

MTERF4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31892-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using MTERF4 Polyclonal antibody (31892-1-AP)

    WB analysis using 31892-1-AP (same clone as 31892-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31892-1-AP (MTERFD2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31892-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31892-1-PBS bindet in WB, Indirect ELISA MTERF4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MTERF4 fusion protein Ag32334
Vollständiger Name MTERF domain containing 2
Berechnetes Molekulargewicht44 kDa
Beobachtetes Molekulargewicht37 kDa
GenBank-ZugangsnummerNM_182501
Gene symbol MTERFD2
Gene ID (NCBI) 130916
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The MTERF protein family plays a key role in controlling mitochondrial DNA gene expression in mammals. Mitochondrial transcription termination factor 4 (MTERF4, also known as MTERFD2) regulates mitochondrial ribosome biogenesis and translation (PMID: 21531335). It can form a stoichiometric complex with the ribosomal RNA methyl-transferase NSUN4 and is necessary for the recruitment of this factor to the large ribosomal subunit. Loss of MTERF4 leads to defective ribosomal assembly and a drastic reduction in translation (PMID: 21531335).