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MTMR15/FAN1 Polyklonaler Antikörper

MTMR15/FAN1 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17600-1-PBS

Synonyme

MTMR15, EC:3.1.21.-, FAN1, FANCD2/FANCI-associated nuclease 1, Fanconi-associated nuclease 1

Filter:
  • Western Blot (WB) analysis of various lysates using MTMR15/FAN1 Polyclonal antibody (17600-1-AP)

    WB analysis using 17600-1-AP (same clone as 17600-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17600-1-AP (MTMR15 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17600-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human spleen tissue using MTMR15/FAN1 Polyclonal antibody (17600-1-AP)

    WB analysis of human spleen using 17600-1-AP (same clone as 17600-1-PBS)

    human spleen tissue were subjected to SDS PAGE followed by western blot with 17600-1-AP (MTMR15 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17600-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of HeLa cells using MTMR15/FAN1 Polyclonal antibody (17600-1-AP)

    IP experiment of HeLa using 17600-1-AP (same clone as 17600-1-PBS)

    IP result of anti-MTMR15 (IP:17600-1-AP, 4ug; Detection:17600-1-AP 1:300) with HeLa cells lysate 2800 ug. This data was developed using the same antibody clone with 17600-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17600-1-PBS bindet in WB, IP, Indirect ELISA MTMR15/FAN1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MTMR15/FAN1 fusion protein Ag11651
Vollständiger Name myotubularin related protein 15
Berechnetes Molekulargewicht 60 kDa, 114 kDa
Beobachtetes Molekulargewicht 63-68 kDa, 120-140 kDa
GenBank-ZugangsnummerBC047882
Gene symbol MTMR15
Gene ID (NCBI) 22909
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MTMR15, also named as FAN1 and KIAA1018, is a nuclease required for the repair of DNA interstrand cross-links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. It is specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, probably in the resolution of homologous recombination intermediates. MTMR15 has some isoforms with MW 114 kDa and 60 kDa. The MW will be migrated to 120-140 kDa and 63-68 kDa with modification.