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MTTP/MTP Polyklonaler Antikörper

MTTP/MTP Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 23940-1-PBS

Synonyme

MTTP, MTP

Filter:
  • Western Blot (WB) analysis of various lysates using MTTP/MTP Polyclonal antibody (23940-1-AP)

    WB analysis using 23940-1-AP (same clone as 23940-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23940-1-AP (MTTP antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. Negative control: human skeletal muscle tissue, mouse kidney tissue, mouse skeletal muscle tissue, mouse spleen tissue. This data was developed using the same antibody clone with 23940-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

23940-1-PBS bindet in WB, Indirect ELISA MTTP/MTP und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MTTP/MTP fusion protein Ag21045
Vollständiger Name microsomal triglyceride transfer protein
Berechnetes Molekulargewicht151aa,17 kDa; 894aa,99 kDa
Beobachtetes Molekulargewicht 90-100 kDa
GenBank-ZugangsnummerBC062696
Gene symbol MTTP
Gene ID (NCBI) 4547
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-affinitätsgereinigt
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MTTP, also known as MTP, belongs to the lipid transfer protein family and forms a heterodimeric complex with protein disulfide isomerase (PDI) to perform lipid transfer functions. MTTP is isolated as a soluble protein from the lumen of a microsomal fraction of liver and intestine. MTTP assembles triglycerides and apoB in the liver and intestine and subsequently produces apoB-containing lipoproteins. Deficiency in MTTP can cause abetalipoproteinemia, characterized by the absence of apoB-containing lipoproteins from the circulatory system(PMID: 10946006, 23475612).