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MTUS1 Rekombinanter Antikörper

MTUS1 Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242537B7

Kat-Nr. : 85117-4-PBS

Synonyme

ATIP, ATBP, AT2 receptor-binding protein, AT2 receptor binding protein, Angiotensin-II type 2 receptor-interacting protein

Filter:
  • Western Blot (WB) analysis of various lysates using MTUS1 Recombinant antibody (85117-4-RR)

    WB analysis using 85117-4-RR (same clone as 85117-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85117-4-RR (MTUS1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85117-4-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of PC-3 cells using MTUS1 Recombinant antibody (85117-4-RR)

    IF Staining of PC-3 using 85117-4-RR (same clone as 85117-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed PC-3 cells using MTUS1 antibody (85117-4-RR, Clone: 242537B7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 85117-4-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85117-4-PBS bindet in WB, IF/ICC, Indirect ELISA MTUS1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen MTUS1 fusion protein Ag4242
Vollständiger Name mitochondrial tumor suppressor 1
Berechnetes Molekulargewicht 51 kDa, 141 kDa
Beobachtetes Molekulargewicht 50 kDa
GenBank-ZugangsnummerBC033842
Gene symbol MTUS1
Gene ID (NCBI) 57509
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MTUS1, also named as ATBP, ATIP, GK1, KIAA1288 and MTSG1, Belongs to the MTUS1 family. It cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. MTUS1 may be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth. MTUS1 up-regulation during cellular transition from proliferation to quiescence and differentiation. It is a potential tumor suppressor gene located at chromosome 8p21.3.22, near marker D8S254. According to the functional data and intracellular localization, MTUS1 also named as mitochondrial tumor suppressor gene 1 (MTSG1). One main feature common to all ATIP members is the presence of a large C-terminal coiled-coil domain that allows homo- and hetero-dimerization of these proteins. (PMID:12692079, 15123706).