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MUPP1 Polyklonaler Antikörper

MUPP1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22583-1-PBS

Synonyme

MPDZ

Filter:
  • Western Blot (WB) analysis of various lysates using MUPP1 Polyclonal antibody (22583-1-AP)

    WB analysis using 22583-1-AP (same clone as 22583-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22583-1-AP (MUPP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22583-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22583-1-PBS bindet in WB, Indirect ELISA MUPP1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MUPP1 fusion protein Ag18222
Vollständiger Name multiple PDZ domain protein
Berechnetes Molekulargewicht 2070 aa, 222 kDa
Beobachtetes Molekulargewicht 250 kDa
GenBank-ZugangsnummerBC140793
Gene symbol MPDZ
Gene ID (NCBI) 8777
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The PDZ domain is a protein motif that mediates protein-protein interactions. MUPP1(multi-PDZ domain protein-1) has 13 PDZ domains, each containing the structural characteristics of a prototypic PDZ motif, but lacks a catalytic domain. MUPP1 belongs to the PDZ domain protein family and is a structural homologant of PATJ (PALS1-associated tight-linking protein) (PMID: 23880463). MUPP1 is a scaffold protein and plays an important role in cytoskeletal organization, cell polarity, and cell proliferation(PMID: 25662616). Mutations in MUPP1 are associated with congenital hydrocephalus(PMID: 23240096).