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MVK Monoklonaler Antikörper

MVK Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2F1D3

Kat-Nr. : 67820-1-PBS

Synonyme

FLJ96772, LRBP, mevalonate kinase, MK, MVK, MVLK

Filter:
  • Western Blot (WB) analysis of various lysates using MVK Monoclonal antibody (67820-1-Ig)

    WB analysis using 67820-1-Ig (same clone as 67820-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67820-1-Ig (MVK antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67820-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of U2OS cells using MVK Monoclonal antibody (67820-1-Ig)

    WB analysis of U2OS using 67820-1-Ig (same clone as 67820-1-PBS)

    U2OS cells were subjected to SDS PAGE followed by western blot with 67820-1-Ig (MVK antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67820-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67820-1-PBS bindet in WB, Indirect ELISA MVK und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen MVK fusion protein Ag28887
Vollständiger Name mevalonate kinase
Berechnetes Molekulargewicht 396 aa, 42 kDa
Beobachtetes Molekulargewicht 42 kDa
GenBank-ZugangsnummerBC016140
Gene symbol MVK
Gene ID (NCBI) 4598
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MVK (Mevalonate kinase) is a 42 kDa cytoplasmic protein that belongs to the GHMP kinase family. Mevalonate kinase catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Defects in mevalonate kinase can cause mevalonic aciduria (MEVA). It is an accumulation of mevalonic acid which causes a variety of symptoms such as psychomotor retardation, dysmorphic features, cataracts, hepatosplenomegaly, lymphadenopathy, anemia, hypotonia, myopathy and ataxia.