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MX2 Polyklonaler Antikörper

MX2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13278-1-PBS

Synonyme

p78-related protein, p78 related protein, Myxovirus resistance protein 2, MXB, Interferon-regulated resistance GTP-binding protein MxB

Filter:
  • Western Blot (WB) analysis of various lysates using MX2 Polyclonal antibody (13278-1-AP)

    WB analysis using 13278-1-AP (same clone as 13278-1-PBS)

    Untreated and IFN beta treated THP-1 cell lysates were subjected to SDS PAGE followed by western blot with 13278-1-AP (MX2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13278-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human stomach tissue using MX2 Polyclonal antibody (13278-1-AP)

    IHC staining of human stomach using 13278-1-AP (same clone as 13278-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 13278-1-AP (MX2 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13278-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13278-1-PBS bindet in WB, IHC, Indirect ELISA MX2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen MX2 fusion protein Ag4020
Vollständiger Name myxovirus (influenza virus) resistance 2 (mouse)
Berechnetes Molekulargewicht 715 aa, 82 kDa
Beobachtetes Molekulargewicht 70-82 kDa
GenBank-ZugangsnummerBC035293
Gene symbol MX2
Gene ID (NCBI) 4600
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Myxovirus resistance 2 (MX2, also known as MxB) is a member of both the dynamin family and the family of large GTPases. MX2 is an interferon-stimulated gene that inhibits the nuclear import of HIV-1 and interacts with the viral capsid and cellular nuclear transport machinery. MX2 mediates the effects of IFN signaling in a cell type and context-dependent manner that can influence cells sensitivity to MAPK pathway targeted therapies. MX2 is also associated with the tumorigenesis process in melanoma(PMID: 33734579).