MYD88 Polyklonaler Antikörper

MYD88 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29946-1-PBS

Synonyme

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  WB analysis using 29946-1-AP (same clone as 29946-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29946-1-AP (MYD88 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29946-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 29946-1-AP (same clone as 29946-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 29946-1-AP (MYD88 antibody) at dilution of 1:800 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29946-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 29946-1-AP (same clone as 29946-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 29946-1-AP (MYD88 antibody) at dilution of 1:800 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29946-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

29946-1-PBS bindet in WB, IHC, Indirect ELISA MYD88 und zeigt Reaktivität mit Maus, Ratten

• Getestete Reaktivität: Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: MYD88 fusion protein Ag30662
• Vollständiger Name: myeloid differentiation primary response gene 88
• Berechnetes Molekulargewicht: 34 kDa
• Beobachtetes Molekulargewicht: 29-34 kDa
• GenBank-Zugangsnummer: NM_010851
• Gene symbol: Myd88
• Gene ID (NCBI): 17874
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the interleukin-1 receptor (IL-1R) and most Toll-like receptors (TLRs), which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis. MYD88 is detected in bone marrow.