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MYSM1-Specific Rekombinanter Antikörper

MYSM1-Specific Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

243158A9

Kat-Nr. : 85927-1-PBS

Synonyme

MYSM1, 2A DUB, 2ADUB, 2A-DUB, Deubiquitinase MYSM1

Filter:
  • Western Blot (WB) analysis of various lysates using MYSM1-Specific Recombinant antibody (85927-1-RR)

    WB analysis using 85927-1-RR (same clone as 85927-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85927-1-RR (MYSM1-Specific antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85927-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using MYSM1-Specific Recombinant antibody (85927-1-RR)

    WB analysis using 85927-1-RR (same clone as 85927-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85927-1-RR (MYSM1-Specific antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85927-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of NIH/3T3 cells using MYSM1-Specific Recombinant antibody (85927-1-RR)

    WB analysis of NIH/3T3 using 85927-1-RR (same clone as 85927-1-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 85927-1-RR (MYSM1-Specific antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85927-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85927-1-PBS bindet in WB, Indirect ELISA MYSM1-Specific und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name Myb-like, SWIRM and MPN domains 1
Berechnetes Molekulargewicht 95 kDa
Beobachtetes Molekulargewicht 81 kDa
GenBank-ZugangsnummerNM_001085487
Gene symbol MYSM1
Gene ID (NCBI) 114803
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MYSM1, also named as KIAA1915, belongs to the peptidase M67A family and MYSM1 subfamily. MYSM1 is a metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. MYSM1 acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. It catalyzes the reaction: Ubiquitin C-terminal thioester + H2O = ubiquitin + a thiol. MYSM1 is a marker of cancer. The antibody is specific to MYSM1.