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MYST2 Monoklonaler Antikörper

MYST2 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

1C1B1

Kat-Nr. : 68525-1-PBS

Synonyme

1C1B1, EC:2.3.1.48, HBO1, HBOa, Histone acetyltransferase KAT7

Filter:
  • Western Blot (WB) analysis of various lysates using MYST2 Monoclonal antibody (68525-1-Ig)

    WB analysis using 68525-1-Ig (same clone as 68525-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68525-1-Ig (MYST2 antibody) at dilution of 1:4900 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68525-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68525-1-PBS bindet in WB, ELISA MYST2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen MYST2 fusion protein Ag5166
Vollständiger Name MYST histone acetyltransferase 2
Berechnetes Molekulargewicht 611 aa, 71 kDa
Beobachtetes Molekulargewicht83 kDa
GenBank-ZugangsnummerBC032640
Gene symbol MYST2
Gene ID (NCBI) 11143
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MYST2, also named as HBO1, HBOa MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, belongs to the MYST (SAS/MOZ) family. It specifically represses AR mediated transcription. MYST2 is a candidate oncogene. It enhances the anchorage-independent growth of breast cancer cells.(PMID:19372580) MYST2 is a histone acetyltransferase (HAT) which could exert oncogenic function in breast cancer. It is an important downstream molecule of ERa, and ERK1/2 signaling pathway may involved in the expression of HBO1 increased by E2.