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MYST2 Rekombinanter Antikörper

MYST2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251386C9

Kat-Nr. : 86486-1-PBS

Synonyme

EC:2.3.1.48, HBO1, HBOa, Histone acetyltransferase KAT7, KAT 7

Filter:
  • Western Blot (WB) analysis of various lysates using MYST2 Recombinant antibody (86486-1-RR)

    WB analysis using 86486-1-RR (same clone as 86486-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86486-1-RR (MYST2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86486-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86486-1-RR

    Affinity and Kinetic Characterization of 86486-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86486-1-RR against Human MYST2 were performed. The affinity constant is 1.94 nM.

Geprüfte Anwendungen

Produktinformation

86486-1-PBS bindet in WB, Indirect ELISA MYST2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen MYST2 fusion protein Ag4693
Vollständiger Name MYST histone acetyltransferase 2
Berechnetes Molekulargewicht 611 aa, 71 kDa
Beobachtetes Molekulargewicht71-75 kDa
GenBank-ZugangsnummerBC032640
Gene symbol MYST2
Gene ID (NCBI) 11143
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MYST2, also named as HBO1, HBOa MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, belongs to the MYST (SAS/MOZ) family. It specifically represses AR mediated transcription. MYST2 is a candidate oncogene. It enhances the anchorage-independent growth of breast cancer cells.(PMID:19372580) MYST2 is a histone acetyltransferase (HAT) which could exert oncogenic function in breast cancer. It is an important downstream molecule of ERa, and ERK1/2 signaling pathway may involved in the expression of HBO1 increased by E2.