CD11c Monoklonaler Antikörper

CD11c Monoklonal Antikörper für Single Cell (Intra), Single Cell

Wirt / Isotyp

Maus / IgG1, kappa

Getestete Reaktivität

human

Anwendung

Single Cell (Intra), Single Cell

Konjugation

5CFLX Fluorescent Dye

CloneNo.

3.9

Kat-Nr. : G65086-1-5C

Synonyme

CD11C, Integrin alpha X, ITGAX, Leu M5, SLEB6

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  Single Cell Sequencing experiment G65086-1-5C on Resting PBMC

  G65086-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

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  Single Cell Sequencing experiment G65086-1-5C on PBMC treated with 4hr LPS + TI

  G65086-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

• 

  Single Cell Sequencing experiment G65086-1-5C on Resting PBMC

  G65086-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Stain-Fix protocol.

• 

  Single Cell Sequencing experiment G65086-1-5C on PBMC treated with 4hr LPS + TI

  G65086-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Stain-Fix protocol.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in Single Cell (Intra): 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product
• Erfolgreiche Detektion in Single Cell: 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product

Empfohlene Verdünnung

• SINGLE CELL (INTRA): SINGLE CELL (INTRA) : <0.5ug/test
• SINGLE CELL: SINGLE CELL : <0.5ug/test

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

G65086-1-5C bindet in Single Cell (Intra), Single Cell CD11c und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1, kappa
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Rheumatoide Synovialzellen und humane Monozyten
• Vollständiger Name: integrin, alpha X (complement component 3 receptor 4 subunit)
• Berechnetes Molekulargewicht: 1169 aa, 129 kDa
• GenBank-Zugangsnummer: BC038237
• Gene symbol: CD11c
• Gene ID (NCBI): 3687
• Konjugation: 5CFLX Fluorescent Dye
• Form: Liquid
• Lagerungspuffer: PBS with 1mM EDTA and 0.09% sodium azide
• Lagerungsbedingungen: 2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).