CD16 Monoklonaler Antikörper
CD16 Monoklonal Antikörper für Single Cell (Intra), Single Cell
Wirt / Isotyp
Maus / IgG1, kappa
Getestete Reaktivität
human
Anwendung
Single Cell (Intra), Single Cell
Konjugation
5CFLX Fluorescent Dye
CloneNo.
3G8
Kat-Nr. : G65090-1-5C
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in Single Cell (Intra) | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Erfolgreiche Detektion in Single Cell | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Empfohlene Verdünnung
Anwendung | Verdünnung |
---|---|
SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
SINGLE CELL | SINGLE CELL : <0.5ug/test |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
G65090-1-5C bindet in Single Cell (Intra), Single Cell CD16 und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG1, kappa |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | k.A. |
Vollständiger Name | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
Berechnetes Molekulargewicht | 254 aa, 29 kDa |
GenBank-Zugangsnummer | BC017865 |
Gene symbol | CD16a |
Gene ID (NCBI) | 2214 |
Konjugation | 5CFLX Fluorescent Dye |
Form | Liquid |
Reinigungsmethode | |
Lagerungspuffer | PBS with 1mM EDTA and 0.09% sodium azide |
Lagerungsbedingungen | 2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B. Clone 3G8 recognizes both the CD16a and CD16b (PMID: 7592758).