CD19 Monoklonaler Antikörper

CD19 Monoklonal Antikörper für Single Cell (Intra), Single Cell

Wirt / Isotyp

Maus / IgG1, kappa

Getestete Reaktivität

human

Anwendung

Single Cell (Intra), Single Cell

Konjugation

5CFLX Fluorescent Dye

CloneNo.

HIB19

Kat-Nr. : G65110-1-5C

Synonyme

B lymphocyte antigen CD19, B4, CD19, CD19 molecule, Differentiation antigen CD19, T cell surface antigen Leu 12



Geprüfte Anwendungen

Erfolgreiche Detektion in Single Cell (Intra)10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product
Erfolgreiche Detektion in Single Cell10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product

Empfohlene Verdünnung

AnwendungVerdünnung
SINGLE CELL (INTRA)SINGLE CELL (INTRA) : <0.5ug/test
SINGLE CELLSINGLE CELL : <0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

G65110-1-5C bindet in Single Cell (Intra), Single Cell CD19 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen k.A.
Vollständiger Name CD19 molecule
Berechnetes Molekulargewicht 556 aa, 61 kDa
GenBank-ZugangsnummerBC006338
Gene symbol CD19
Gene ID (NCBI) 930
Konjugation 5CFLX Fluorescent Dye
Form Liquid
Reinigungsmethode
Lagerungspuffer PBS with 1mM EDTA and 0.09% sodium azide
Lagerungsbedingungen2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908).