CD19 Monoklonaler Antikörper
CD19 Monoklonal Antikörper für Single Cell (Intra), Single Cell
Wirt / Isotyp
Maus / IgG1, kappa
Getestete Reaktivität
human
Anwendung
Single Cell (Intra), Single Cell
Konjugation
5CFLX Fluorescent Dye
CloneNo.
HIB19
Kat-Nr. : G65110-1-5C
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in Single Cell (Intra) | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Erfolgreiche Detektion in Single Cell | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Empfohlene Verdünnung
Anwendung | Verdünnung |
---|---|
SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
SINGLE CELL | SINGLE CELL : <0.5ug/test |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
G65110-1-5C bindet in Single Cell (Intra), Single Cell CD19 und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG1, kappa |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | k.A. |
Vollständiger Name | CD19 molecule |
Berechnetes Molekulargewicht | 556 aa, 61 kDa |
GenBank-Zugangsnummer | BC006338 |
Gene symbol | CD19 |
Gene ID (NCBI) | 930 |
Konjugation | 5CFLX Fluorescent Dye |
Form | Liquid |
Reinigungsmethode | |
Lagerungspuffer | PBS with 1mM EDTA and 0.09% sodium azide |
Lagerungsbedingungen | 2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908).