CD21 Monoklonaler Antikörper
CD21 Monoklonal Antikörper für Single Cell (Intra), Single Cell
Wirt / Isotyp
Maus / IgG1, kappa
Getestete Reaktivität
human
Anwendung
Single Cell (Intra), Single Cell
Konjugation
5CFLX Fluorescent Dye
CloneNo.
BU32
Kat-Nr. : G65198-1-5C
Synonyme
Geprüfte Anwendungen
| Erfolgreiche Detektion in Single Cell (Intra) | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product | 
| Erfolgreiche Detektion in Single Cell | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product | 
Empfohlene Verdünnung
| Anwendung | Verdünnung | 
|---|---|
| SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test | 
| SINGLE CELL | SINGLE CELL : <0.5ug/test | 
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Produktinformation
G65198-1-5C bindet in Single Cell (Intra), Single Cell CD21 und zeigt Reaktivität mit human
| Getestete Reaktivität | human | 
| Wirt / Isotyp | Maus / IgG1, kappa | 
| Klonalität | Monoklonal | 
| Typ | Antikörper | 
| Immunogen | k.A. | 
| Vollständiger Name | complement component (3d/Epstein Barr virus) receptor 2 | 
| Berechnetes Molekulargewicht | 1092 aa, 119 kDa | 
| GenBank-Zugangsnummer | BC136394 | 
| Gene symbol | CD21 | 
| Gene ID (NCBI) | 1380 | 
| Konjugation | 5CFLX Fluorescent Dye | 
| Form | Liquid | 
| Reinigungsmethode | |
| Lagerungspuffer | PBS with 1mM EDTA and 0.09% sodium azide | 
| Lagerungsbedingungen | 2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA. | 
Hintergrundinformationen
CD21, also known as complement receptor type 2 (CR2), complement C3d receptor, and Epstein-Barr virus receptor, is a transmembrane protein that contains a small cytoplasmic domain, a transmembrane region and an extracellular domain consisting of 15 tandem short consensus repeat sequences (PMID: 6230668; 2551147). It is expressed on B cells, follicular dendritic cells, thymocytes and a subset of peripheral T cells (PMID: 26119182). CD21 binds complement fragments C3d, C3dg and iC3b and acts as a receptor for the Epstein-Barr virus (PMID: 7753047). On B cells, together with CD19 and CD81, CD21 forms a complex that functions as a co-receptor to the BCR (PMID: 7542009). It is involved in B cells activation and functions.



