CD31 Monoklonaler Antikörper

CD31 Monoklonal Antikörper für Single Cell (Intra), Single Cell

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

Single Cell (Intra), Single Cell

Konjugation

5CFLX Fluorescent Dye

CloneNo.

3F8E2

Kat-Nr. : G66065-2-5C

Synonyme

CD31, EndoCAM, FLJ58394, GPIIA, PECA1, PECAM 1, PECAM1, VEC marker



Geprüfte Anwendungen

Erfolgreiche Detektion in Single Cell (Intra)10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product
Erfolgreiche Detektion in Single Cell10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product

Empfohlene Verdünnung

AnwendungVerdünnung
SINGLE CELL (INTRA)SINGLE CELL (INTRA) : <0.5ug/test
SINGLE CELLSINGLE CELL : <0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

G66065-2-5C bindet in Single Cell (Intra), Single Cell CD31 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen CD31 fusion protein Ag19730
Vollständiger Name platelet/endothelial cell adhesion molecule
Berechnetes Molekulargewicht 83 kDa
GenBank-ZugangsnummerBC022512
Gene symbol CD31
Gene ID (NCBI) 5175
Konjugation 5CFLX Fluorescent Dye
Form Liquid
Reinigungsmethode
Lagerungspuffer PBS with 1mM EDTA and 0.09% sodium azide
Lagerungsbedingungen2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).