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CD35 Monoklonaler Antikörper

CD35 Monoklonal Antikörper für Single Cell (Intra), Single Cell

Wirt / Isotyp

Maus / IgG1, kappa

Getestete Reaktivität

human

Anwendung

Single Cell (Intra), Single Cell

Konjugation

5CFLX Fluorescent Dye

CloneNo.

E11

Kat-Nr. : G65254-1-5C

Synonyme

C3b/C4b receptor, C3BR, CD35, Complement receptor type 1, CR1, KN

Filter:
  • Single Cell Sequencing experiment G65254-1-5C on Resting PBMC

    Single Cell Sequencing experiment G65254-1-5C on Resting PBMC

    G65254-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

  • Single Cell Sequencing experiment G65254-1-5C on PBMC treated with 4hr LPS + TI

    Single Cell Sequencing experiment G65254-1-5C on PBMC treated with 4hr LPS + TI

    G65254-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

  • Single Cell Sequencing experiment G65254-1-5C on Resting PBMC

    Single Cell Sequencing experiment G65254-1-5C on Resting PBMC

    G65254-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Stain-Fix protocol.

  • Single Cell Sequencing experiment G65254-1-5C on PBMC treated with 4hr LPS + TI

    Single Cell Sequencing experiment G65254-1-5C on PBMC treated with 4hr LPS + TI

    G65254-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Stain-Fix protocol.

Geprüfte Anwendungen

Erfolgreiche Detektion in Single Cell (Intra)10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product
Erfolgreiche Detektion in Single Cell10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product

Empfohlene Verdünnung

AnwendungVerdünnung
SINGLE CELL (INTRA)SINGLE CELL (INTRA) : <0.5ug/test
SINGLE CELLSINGLE CELL : <0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

G65254-1-5C bindet in Single Cell (Intra), Single Cell CD35 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen Human CD35 from Acute monocytic leukemia cells and normal blood monocytes
Vollständiger Name complement component (3b/4b) receptor 1 (Knops blood group)
Berechnetes Molekulargewicht 224 kDa
GenBank-ZugangsnummerNM_000573
Gene symbol CR1
Gene ID (NCBI) 1378
Konjugation 5CFLX Fluorescent Dye
Form Liquid
Reinigungsmethode
Lagerungspuffer PBS with 1mM EDTA and 0.09% sodium azide
Lagerungsbedingungen2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD35, also known as complement receptor type 1 (CR1) or C3b/C4b receptor, is a single-chain glycoprotein consisting of 30 repeating homologous protein domains known as short consensus repeats (~60 amino acids each) followed by transmembrane and cytoplasmic domains (PMID: 8765013). CD35 is variably expressed by granulocytes, monocytes, B cells, some T cells, erythrocytes, follicular dendritic cells, Langerhans cells, and glomerular podocytes (PMID: 19004497). CD35 acts as a receptor for C3b and C4b and plays important roles in the regulation of the complement cascade and clearance of immune complexes.