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CD40 Monoklonaler Antikörper

CD40 Monoklonal Antikörper für Single Cell (Intra)

Wirt / Isotyp

Maus / IgG1, kappa

Getestete Reaktivität

human

Anwendung

Single Cell (Intra)

Konjugation

5CFLX Fluorescent Dye

CloneNo.

G28.5

Kat-Nr. : G65103-1-5C

Synonyme

B cell surface antigen CD40, Bp50, CD40, CD40L receptor, CDW40, p50, TNFRSF5

Filter:
  • Single Cell Sequencing experiment G65103-1-5C on Resting PBMC

    Single Cell Sequencing experiment G65103-1-5C on Resting PBMC

    G65103-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

  • Single Cell Sequencing experiment G65103-1-5C on PBMC treated with 4hr LPS + TI

    Single Cell Sequencing experiment G65103-1-5C on PBMC treated with 4hr LPS + TI

    G65103-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

Geprüfte Anwendungen

Erfolgreiche Detektion in Single Cell (Intra)10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product

Empfohlene Verdünnung

AnwendungVerdünnung
SINGLE CELL (INTRA)SINGLE CELL (INTRA) : <0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

G65103-1-5C bindet in Single Cell (Intra) CD40 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen k.A.
Vollständiger Name CD40 molecule, TNF receptor superfamily member 5
Berechnetes Molekulargewicht 277 aa, 31 kDa
GenBank-ZugangsnummerBC012419
Gene symbol CD40
Gene ID (NCBI) 958
Konjugation 5CFLX Fluorescent Dye
Form Liquid
Reinigungsmethode
Lagerungspuffer PBS with 1mM EDTA and 0.09% sodium azide
Lagerungsbedingungen2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CD40, also named as TNFRSF5 and Bp50, is a type I transmembrane protein that belongs to the tumor necrosis factor-R (TNF-R) family (PMID: 10647992). CD40 is expressed on B cells, dendritic cells (DCs), monocytes, platelets, and macrophages as well as by non-hematopoietic cells such as myofibroblasts, fibroblasts, epithelial, and endothelial cells (PMID: 19426221). It is a receptor for TNFSF5/CD40LG. CD40L/CD40 interactions are essential for immunoglobulin (Ig) isotype switching, germinal center formation and the development of B cell memory (PMID: 7516405; 11675497).