CD54 (ICAM-1) Monoklonaler Antikörper
CD54 (ICAM-1) Monoklonal Antikörper für Single Cell (Intra)
Wirt / Isotyp
Maus / IgG1, kappa
Getestete Reaktivität
human
Anwendung
Single Cell (Intra)
Konjugation
5CFLX Fluorescent Dye
CloneNo.
15.2
Kat-Nr. : G65075-1-5C
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in Single Cell (Intra) | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Empfohlene Verdünnung
Anwendung | Verdünnung |
---|---|
SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
G65075-1-5C bindet in Single Cell (Intra) CD54 (ICAM-1) und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG1, kappa |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | Rheumatoide Synovialzellen und humane Monozyten |
Vollständiger Name | intercellular adhesion molecule 1 |
Berechnetes Molekulargewicht | 90 kDa |
GenBank-Zugangsnummer | BC015969 |
Gene symbol | ICAM-1 |
Gene ID (NCBI) | 3383 |
Konjugation | 5CFLX Fluorescent Dye |
Form | Liquid |
Reinigungsmethode | |
Lagerungspuffer | PBS with 1mM EDTA and 0.09% sodium azide |
Lagerungsbedingungen | 2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).