CD54 (ICAM-1) Monoklonaler Antikörper

CD54 (ICAM-1) Monoklonal Antikörper für Single Cell (Intra)

Wirt / Isotyp

Maus / IgG1, kappa

Getestete Reaktivität

human

Anwendung

Single Cell (Intra)

Konjugation

5CFLX Fluorescent Dye

CloneNo.

15.2

Kat-Nr. : G65075-1-5C

Synonyme

BB2, CD54, ICAM 1, ICAM1, ICAM-1, P3.58



Geprüfte Anwendungen

Erfolgreiche Detektion in Single Cell (Intra)10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product

Empfohlene Verdünnung

AnwendungVerdünnung
SINGLE CELL (INTRA)SINGLE CELL (INTRA) : <0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

G65075-1-5C bindet in Single Cell (Intra) CD54 (ICAM-1) und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1, kappa
Klonalität Monoklonal
Typ Antikörper
Immunogen Rheumatoide Synovialzellen und humane Monozyten
Vollständiger Name intercellular adhesion molecule 1
Berechnetes Molekulargewicht 90 kDa
GenBank-ZugangsnummerBC015969
Gene symbol ICAM-1
Gene ID (NCBI) 3383
Konjugation 5CFLX Fluorescent Dye
Form Liquid
Reinigungsmethode
Lagerungspuffer PBS with 1mM EDTA and 0.09% sodium azide
Lagerungsbedingungen2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).