CD64 Monoklonaler Antikörper

CD64 Monoklonal Antikörper für Single Cell (Intra), Single Cell

Wirt / Isotyp

Maus / IgG1, kappa

Getestete Reaktivität

human

Anwendung

Single Cell (Intra), Single Cell

Konjugation

5CFLX Fluorescent Dye

CloneNo.

10.1

Kat-Nr. : G65253-1-5C

Synonyme

CD64, CD64A, Fc gamma RI, Fc gamma RIA, FCG1, FcgammaRIa, FCGR1, FCGR1A, FCRI, FLJ18345, IGFR1, IgG Fc receptor I

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  Single Cell Sequencing experiment G65253-1-5C on Resting PBMC

  G65253-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

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  Single Cell Sequencing experiment G65253-1-5C on PBMC treated with 4hr LPS + TI

  G65253-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

• 

  Single Cell Sequencing experiment G65253-1-5C on Resting PBMC

  G65253-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Stain-Fix protocol.

• 

  Single Cell Sequencing experiment G65253-1-5C on PBMC treated with 4hr LPS + TI

  G65253-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Stain-Fix protocol.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in Single Cell (Intra): 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product
• Erfolgreiche Detektion in Single Cell: 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product

Empfohlene Verdünnung

• SINGLE CELL (INTRA): SINGLE CELL (INTRA) : <0.5ug/test
• SINGLE CELL: SINGLE CELL : <0.5ug/test

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

G65253-1-5C bindet in Single Cell (Intra), Single Cell CD64 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1, kappa
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Human rheumatoid synovial fluid cells and fibronectin-purified monocytes.
• Vollständiger Name: Fc fragment of IgG, high affinity Ia, receptor (CD64)
• Berechnetes Molekulargewicht: 374 aa, 43 kDa
• GenBank-Zugangsnummer: BC032634
• Gene symbol: FCGR1A
• Gene ID (NCBI): 2209
• Konjugation: 5CFLX Fluorescent Dye
• Form: Liquid
• Lagerungspuffer: PBS with 1mM EDTA and 0.09% sodium azide
• Lagerungsbedingungen: 2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Fcγ receptor comprise a multigene family of integral membrane glycoproteins that exhibit complex activation or inhibitory effects on cell functions after aggregation by complexed immunoglobulin G (IgG) (PMID: 17005690 ). CD64, also known as FcγRIA, is a high-affinity receptor for the Fc region of IgG. It is expressed by monocytes/macrophages, activated neutrophils, dendritic cells, and early myeloid cells (PMID: 23293080; 19642859; 7680917). CD64 functions in both innate and adaptive immune responses.