CXCL8/IL-8 Polyklonaler Antikörper

CXCL8/IL-8 Polyklonal Antikörper für Single Cell (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

Single Cell (Intra)

Konjugation

5CFLX Fluorescent Dye

Kat-Nr. : G17038-1-5C

Synonyme

C X C motif chemokine 8, CXCL8, CXCL8/IL-8, Emoctakin, GCP 1, GCP/IL 8 protein I, GCP/IL 8 protein II, GCP/IL 8 protein III, GCP/IL 8 protein IV, GCP/IL 8 protein V, GCP/IL 8 protein VI, GCP1, IL 8, IL8, IL-8, interleukin 8, LYNAP, MDNCF

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  Single Cell Sequencing experiment G17038-1-5C on Resting PBMC

  G17038-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

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  Single Cell Sequencing experiment G17038-1-5C on PBMC treated with 4hr LPS + TI

  G17038-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in Single Cell (Intra): 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product

Empfohlene Verdünnung

• SINGLE CELL (INTRA): SINGLE CELL (INTRA) : <0.5ug/test

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

G17038-1-5C bindet in Single Cell (Intra) CXCL8/IL-8 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CXCL8/IL-8 fusion protein Ag10552
• Vollständiger Name: interleukin 8
• Berechnetes Molekulargewicht: 99 aa, 11 kDa
• GenBank-Zugangsnummer: BC013615
• Gene symbol: IL-8
• Gene ID (NCBI): 3576
• Konjugation: 5CFLX Fluorescent Dye
• Form: Liquid
• Lagerungspuffer: PBS with 1mM EDTA and 0.09% sodium azide
• Lagerungsbedingungen: 2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Interleukin 8 (IL-8), also known as CXCL8, which is a member of the CXC chemokine family. This chemokine is secreted by a variety of cell types including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, and various tumor cell lines in response to inflammatory stimuli. IL-8 has two primary functions. It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection. IL-8 also induces phagocytosis once they have arrived. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 is also known to be a potent promoter of angiogenesis. IL-8 has been associated with tumor angiogenesis, metastasis, and poor prognosis in breast cancer. IL-8 may present a novel therapeutic target for estrogen driven breast carcinogenesis and tumor progression.