Cyclin D3 Monoklonaler Antikörper
Cyclin D3 Monoklonal Antikörper für Single Cell (Intra)
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human
Anwendung
Single Cell (Intra)
Konjugation
5CFLX Fluorescent Dye
CloneNo.
1F2C6
Kat-Nr. : G66357-1-5C
Synonyme
Geprüfte Anwendungen
| Erfolgreiche Detektion in Single Cell (Intra) | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Produktinformation
G66357-1-5C bindet in Single Cell (Intra) Cyclin D3 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Maus / IgG1 |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | Cyclin D3 fusion protein Ag22825 |
| Vollständiger Name | cyclin D3 |
| Berechnetes Molekulargewicht | 33 kDa |
| GenBank-Zugangsnummer | BC011616 |
| Gene symbol | Cyclin D3 |
| Gene ID (NCBI) | 896 |
| Konjugation | 5CFLX Fluorescent Dye |
| Form | Liquid |
| Reinigungsmethode | |
| Lagerungspuffer | PBS with 1mM EDTA and 0.09% sodium azide |
| Lagerungsbedingungen | 2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Cyclin D3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activitiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.
