Drebrin Monoklonaler Antikörper
Drebrin Monoklonal Antikörper für Single Cell (Intra)
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human
Anwendung
Single Cell (Intra)
Konjugation
5CFLX Fluorescent Dye
CloneNo.
1A12H1
Kat-Nr. : G67589-1-5C
Synonyme
Geprüfte Anwendungen
| Erfolgreiche Detektion in Single Cell (Intra) | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Produktinformation
G67589-1-5C bindet in Single Cell (Intra) Drebrin und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Maus / IgG2a |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | Drebrin fusion protein Ag22635 |
| Vollständiger Name | drebrin 1 |
| GenBank-Zugangsnummer | BC007567 |
| Gene symbol | Drebrin |
| Gene ID (NCBI) | 1627 |
| Konjugation | 5CFLX Fluorescent Dye |
| Form | Liquid |
| Reinigungsmethode | |
| Lagerungspuffer | PBS with 1mM EDTA and 0.09% sodium azide |
| Lagerungsbedingungen | 2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Drebrin (DBN1) is an actin binding and stabilizing protein with roles in endocytosis, formation of dendrite spines in neurons and coordinating cell-cell synapses in immune cells. Preferentially expressed in the brain, it is highly localized in dendritic spines and regulates spine shapes. It has two isoforms that are splice variants, with drebrin A being expressed in neural cells, and drebrin E is present in several other cell types. Recently it has been reported that circulating DBN1 levels correlated with retinal nerve fiber layer defect and may reflect the severity of retinal ganglion cells injury in glaucoma patients.
