LDLR Monoklonaler Antikörper
LDLR Monoklonal Antikörper für Single Cell (Intra)
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human
Anwendung
Single Cell (Intra)
Konjugation
5CFLX Fluorescent Dye
CloneNo.
1A2A3
Kat-Nr. : G66414-1-5C
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in Single Cell (Intra) | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Empfohlene Verdünnung
Anwendung | Verdünnung |
---|---|
SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
G66414-1-5C bindet in Single Cell (Intra) LDLR und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | LDLR fusion protein Ag1236 |
Vollständiger Name | low density lipoprotein receptor |
Berechnetes Molekulargewicht | 95 kDa |
GenBank-Zugangsnummer | BC014514 |
Gene symbol | LDLR |
Gene ID (NCBI) | 3949 |
Konjugation | 5CFLX Fluorescent Dye |
Form | Liquid |
Reinigungsmethode | |
Lagerungspuffer | PBS with 1mM EDTA and 0.09% sodium azide |
Lagerungsbedingungen | 2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.