TBX21,T-bet Polyklonaler Antikörper
TBX21,T-bet Polyklonal Antikörper für Single Cell (Intra)
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
Single Cell (Intra)
Konjugation
5CFLX Fluorescent Dye
Kat-Nr. : G13700-1-5C
Synonyme
Geprüfte Anwendungen
Produktinformation
G13700-1-5C bindet in Single Cell (Intra) TBX21,T-bet und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | TBX21,T-bet fusion protein Ag4618 |
| Vollständiger Name | T-box 21 |
| Berechnetes Molekulargewicht | 535 aa, 58 kDa |
| GenBank-Zugangsnummer | BC039739 |
| Gene symbol | TBX21/T-bet |
| Gene ID (NCBI) | 30009 |
| Konjugation | 5CFLX Fluorescent Dye |
| Form | Liquid |
| Reinigungsmethode | |
| Lagerungspuffer | PBS with 1mM EDTA and 0.09% sodium azide |
| Lagerungsbedingungen | 2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
TBX21 is a transcription factor that drives the Th1 immune response primarily through promoting expression of the IFN-γ gene. TBX21 initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs. It has also been shown to play an influential role in inflammatory processes such as inflammatory bowel disease, autoimmune diseases such as rheumatoid arthritis, and immune-mediated conditions like asthma.
