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TGFBI / BIGH3 Monoklonaler Antikörper

TGFBI / BIGH3 Monoklonal Antikörper für Single Cell (Intra)

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

Single Cell (Intra)

Konjugation

5CFLX Fluorescent Dye

CloneNo.

3E11D11

Kat-Nr. : G60007-1-5C

Synonyme

Beta ig h3, BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, Kerato epithelin, LCD1, RGD CAP, TGFBI, TGFBI / BIGH3

Filter:
  • Single Cell Sequencing experiment G60007-1-5C on Resting PBMC

    Single Cell Sequencing experiment G60007-1-5C on Resting PBMC

    G60007-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

  • Single Cell Sequencing experiment G60007-1-5C on PBMC treated with 4hr LPS + TI

    Single Cell Sequencing experiment G60007-1-5C on PBMC treated with 4hr LPS + TI

    G60007-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

Geprüfte Anwendungen

Erfolgreiche Detektion in Single Cell (Intra)10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product

Empfohlene Verdünnung

AnwendungVerdünnung
SINGLE CELL (INTRA)SINGLE CELL (INTRA) : <0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

G60007-1-5C bindet in Single Cell (Intra) TGFBI / BIGH3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen TGFBI / BIGH3 fusion protein Ag0241
Vollständiger Name transforming growth factor, beta-induced, 68kDa
Berechnetes Molekulargewicht 683 aa, 75 kDa
GenBank-ZugangsnummerBC000097
Gene symbol TGFBI
Gene ID (NCBI) 7045
Konjugation 5CFLX Fluorescent Dye
Form Liquid
Reinigungsmethode
Lagerungspuffer PBS with 1mM EDTA and 0.09% sodium azide
Lagerungsbedingungen2-8°C Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TGFBI, also named as BIGH3, Kerato-epithelin and RGD-CAP, binds to type I, II, and IV collagens. TGFBI is an adhesion protein which may play an important role in cell-collagen interactions. In cartilage, it may be involved in endochondral bone formation. TGFBI is an extracellular matrix adaptor protein, it has been reported to be differentially expressed in transformed tissues. TGFBI is a predictive factor of the response to chemotherapy, and suggest the use of TGFBI-derived peptides as possible therapeutic adjuvants for the enhancement of responses to chemotherapy.(PMID:20509890) Defects in TGFBI are the cause of epithelial basement membrane corneal dystrophy (EBMD). Defects in TGFBI are the cause of corneal dystrophy Groenouw type 1 (CDGG1). Defects in TGFBI are the cause of corneal dystrophy lattice type 1 (CDL1). Defects in TGFBI are a cause of corneal dystrophy Thiel-Behnke type (CDTB). Defects in TGFBI are the cause of Reis-Buecklers corneal dystrophy (CDRB). Defects in TGFBI are the cause of lattice corneal dystrophy type 3A (CDL3A). Defects in TGFBI are the cause of Avellino corneal dystrophy (ACD).