• Featured Product
  • KD/KO Validated

N-cadherin Monoklonaler Antikörper

N-cadherin Monoklonal Antikörper für WB, IHC, IF-P, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Kaninchen, Maus, Ratte

Anwendung

WB, IHC, IF-P, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1D8B3

Kat-Nr. : 66219-1-PBS

Synonyme

1D8B3, Cadherin 2, Cadherin-2, CD325, CDH2



Geprüfte Anwendungen

Produktinformation

66219-1-PBS bindet in WB, IHC, IF-P, Cytometric bead array, Indirect ELISA N-cadherin und zeigt Reaktivität mit Hausschwein, human, Kaninchen, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Kaninchen, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen N-cadherin fusion protein Ag4996
Vollständiger Name cadherin 2, type 1, N-cadherin (neuronal)
Berechnetes Molekulargewicht 906 aa, 100 kDa
Beobachtetes Molekulargewicht 130 kDa
GenBank-ZugangsnummerBC036470
Gene symbol N-cadherin
Gene ID (NCBI) 1000
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin), also known as CDH2 (cadherin 2), is a 130-kDa transmembrane protein and a classical member of the cadherin superfamily which also include E-, P-, R-, and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons, endothelial cells and cardiac myocytes (PMID: 11282032; 9508779; 8125202). N-cadherin has functions in early brain morphogenesis, synaptogenesis and synaptic plasticity (PMID: 23321619). The N-cadherin ectodomain can be cleaved, leading to the generation of a 90 kD N-terminal fragment (PMID: 16998833; 17028923).