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N-cadherin Rekombinanter Antikörper

N-cadherin Rekombinant Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

230259H5

Kat-Nr. : 82968-1-PBS

Synonyme

230259H5, Cadherin 2, Cadherin-2, CD325, CDH2



Geprüfte Anwendungen

Produktinformation

82968-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA N-cadherin und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen N-cadherin fusion protein Eg0701
Vollständiger Name cadherin 2, type 1, N-cadherin (neuronal)
Berechnetes Molekulargewicht100 kDa
Beobachtetes Molekulargewicht130 kDa
GenBank-ZugangsnummerNM_001792.4
Gene symbol N-cadherin
Gene ID (NCBI) 1000
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin), also known as CDH2 (cadherin 2), is a 130-kDa transmembrane protein and a classical member of the cadherin superfamily which also includes E-, P-, R-, and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons, endothelial cells and cardiac myocytes (PMID: 11282032; 9508779; 8125202). N-cadherin has functions in early brain morphogenesis, synaptogenesis and synaptic plasticity (PMID: 23321619). The N-cadherin ectodomain can be cleaved, leading to the generation of a 90 kD N-terminal fragment (PMID: 16998833; 17028923).