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N-cadherin Rekombinanter Antikörper
N-cadherin Rekombinant Antikörper für IF/ICC
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
IF/ICC
Konjugation
CoraLite®594 Fluorescent Dye
CloneNo.
230259H5
Kat-Nr. : CL594-82968
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in IF/ICC | HeLa-Zellen, A549-Zellen |
Empfohlene Verdünnung
Anwendung | Verdünnung |
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Immunfluoreszenz (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Produktinformation
CL594-82968 bindet in IF/ICC N-cadherin und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | N-cadherin fusion protein Eg0701 |
Vollständiger Name | cadherin 2, type 1, N-cadherin (neuronal) |
Berechnetes Molekulargewicht | 100 kDa |
Beobachtetes Molekulargewicht | 130 kDa |
GenBank-Zugangsnummer | NM_001792.4 |
Gene symbol | N-cadherin |
Gene ID (NCBI) | 1000 |
Konjugation | CoraLite®594 Fluorescent Dye |
Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA |
Lagerungsbedingungen | Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin), also known as CDH2 (cadherin 2), is a 130-kDa transmembrane protein and a classical member of the cadherin superfamily which also includes E-, P-, R-, and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons, endothelial cells and cardiac myocytes (PMID: 11282032; 9508779; 8125202). N-cadherin has functions in early brain morphogenesis, synaptogenesis and synaptic plasticity (PMID: 23321619). The N-cadherin ectodomain can be cleaved, leading to the generation of a 90 kD N-terminal fragment (PMID: 16998833; 17028923).
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
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IF protocol for CL594 N-cadherin antibody CL594-82968 | Protokoll herunterladen |
STANDARD-PROTOKOLLE | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |