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NAGK Rekombinanter Antikörper

NAGK Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251285C6

Kat-Nr. : 86506-1-PBS

Synonyme

EC:2.7.1.-, EC:2.7.1.59, EC:2.7.1.60, GlcNAc kinase, GNK

Filter:
  • Western Blot (WB) analysis of various lysates using NAGK Recombinant antibody (86506-1-RR)

    WB analysis using 86506-1-RR (same clone as 86506-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86506-1-RR (NAGK antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86506-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86506-1-PBS bindet in WB, Indirect ELISA NAGK und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen NAGK fusion protein Ag7034
Vollständiger Name N-acetylglucosamine kinase
Berechnetes Molekulargewicht 37 kDa
Beobachtetes Molekulargewicht 37 kDa
GenBank-ZugangsnummerBC001029
Gene symbol NAGK
Gene ID (NCBI) 55577
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NAGK, also called N-acetylglucosamine kinase, or GlcNAc kinase, converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. NAGK can suppress the formation of α-syn A53T aggregates in neuronal and non-neuronal cells and suggest aggregation suppression is a general function of NAGK (PMID: 32796833). NAGK is broadly expressed in immune cells and has previously been described to contribute to the hexosamine biosynthetic salvage pathway (PMID: 36002575).