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NAGS Rekombinanter Antikörper

NAGS Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

230279D3

Kat-Nr. : 82963-1-PBS

Synonyme

N-acetylglutamate synthase conserved domain form, EC:2.3.1.1, ARGA, Amino-acid acetyltransferase, AGAS

Filter:
  • Western Blot (WB) analysis of various lysates using NAGS Recombinant antibody (82963-1-RR)

    WB analysis using 82963-1-RR (same clone as 82963-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82963-1-RR (NAGS antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82963-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 82963-1-RR

    Affinity and Kinetic Characterization of 82963-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82963-1-RR against Human NAGS were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

82963-1-PBS bindet in WB, Indirect ELISA NAGS und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen NAGS fusion protein Ag16073
Vollständiger Name N-acetylglutamate synthase
Berechnetes Molekulargewicht 534 aa, 58 kDa
Beobachtetes Molekulargewicht 58 kDa
GenBank-ZugangsnummerBC111713
Gene symbol NAGS
Gene ID (NCBI) 162417
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

N-acetylglutamate synthase, also known as NAGS, is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAGS is the key enzyme for regulating the hepatic urea cycle and is also highly expressed in the kidney and gut. Deficiency of NAGS leads to hyperammonemia due to decreased activity of CPSI deprived of its cofactor NAG(PMID:12459178,12754705).