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Napsin A Monoklonaler Antikörper

Napsin A Monoklonal Antikörper für ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(2)

CloneNo.

2D12A2

Kat-Nr. : 60259-1-Ig

Synonyme

Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, NAP1, NAPA, NAPSA, Napsin 1, Napsin A, napsin A aspartic peptidase, Pronapsin A, SNAPA, TA01/TA02

Geprüfte Anwendungen

Veröffentlichte Anwendungen

IHCSee 1 publications below

Produktinformation

60259-1-Ig bindet in IHC, ELISA Napsin A und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
In Publikationen genannte Reaktivitäthuman
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Napsin A fusion protein Ag9721
Vollständiger Name napsin A aspartic peptidase
Berechnetes Molekulargewicht 420 aa, 45 kDa
Beobachtetes Molekulargewicht 45 kDa
GenBank-ZugangsnummerBC017842
Gene symbol Napsin A
Gene ID (NCBI) 9476
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).

Publikationen

SpeciesApplicationTitle

Nat Commun

Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing γδ T cells.

Authors - Yanyun Du
View Article
humanIHC

Oncotarget

Accelerated hepatocellular carcinoma development in CUL4B transgenic mice.

Authors - Jupeng Yuan
View Article