• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

SLC4A7/NBCn1 Polyklonaler Antikörper

SLC4A7/NBCn1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29442-1-PBS

Synonyme

NBCn1, SLC4A7, NBC2, NBC3

Filter:
  • Western Blot (WB) analysis of various lysates using SLC4A7/NBCn1 Polyclonal antibody (29442-1-AP)

    WB analysis using 29442-1-AP (same clone as 29442-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29442-1-AP (SLC4A7/NBCn1 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29442-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

29442-1-PBS bindet in WB, Indirect ELISA SLC4A7/NBCn1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SLC4A7/NBCn1 fusion protein Ag30545
Vollständiger Name solute carrier family 4, sodium bicarbonate cotransporter, member 7
Berechnetes Molekulargewicht 136 kDa
Beobachtetes Molekulargewicht 136 kDa
GenBank-ZugangsnummerNM_003615
Gene symbol NBCn1/SLC4A7
Gene ID (NCBI) 9497
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SLC4A7 also known as NBCn1, NBC3, NBC2, is an electroneutral Na(+)/HCO(3)(-) cotransporter (PMID: 14736710). SLC4A7 mediates the coupled movement of sodium and bicarbonate ions across the plasma membrane. SLC4A7 plays a key role in macrophage acidification, mediating bicarbonate import into the cytoplasm which is crucial for net acid extrusion and maintenance of cytoplasmic pH during phagocytosis (PubMed:29779931). SLC4A7 is expressed in testis, spleen, and retina. SLC4A7 may be a major regulator of extracellular pH of retina where light stimulation produces an extracellular alkalization and may contribute as a solute transporter to the prevention of retinal detachment(PMID: 9610397).