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NCAM1/CD56 Rekombinanter Antikörper

NCAM1/CD56 Rekombinant Antikörper für Sandwich ELISA, Indirect ELISA, Sample test

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

Sandwich ELISA, Indirect ELISA, Sample test

Konjugation

Unkonjugiert

CloneNo.

240078A7

Kat-Nr. : 83365-5-PBS

Synonyme

CD56, NCAM1, 240078A7, NCAM 1, NCAM

Filter:
  • Sandwich ELISA standard curve of MP00393-4

    Sandwich ELISA standard curve of MP00393-4

    Sandwich ELISA standard curve of MP00393-4, Human NCAM1/CD56 Monoclonal Matched Antibody Pair - PBS only. 83365-5-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Eg31816. 83365-4-PBS was HRP conjugated as the detection antibody. Range: 0.156-10 ng/mL.

  • Sample test of MP00393-4

    Sample test of MP00393-4

    The NCAM1/CD56 concentration of Human cerebrospinal fluid (CSF) samples were determined to be 127.3 ng/mL.

  • Sample test of MP00393-4

    Sample test of MP00393-4

    Serum of sixteen individual healthy human donors were measured. The NCAM1/CD56 concentration of detected samples was determined to be 1.2 ug/mL with a range of 0.7 - 1.9 ug/mL.

Geprüfte Anwendungen

Produktinformation

83365-5-PBS bindet in Sandwich ELISA, Indirect ELISA, Sample test NCAM1/CD56 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name neural cell adhesion molecule 1
Berechnetes Molekulargewicht 95 kDa
GenBank-ZugangsnummerBC047244
Gene symbol NCAM1
Gene ID (NCBI) 4684
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Neural cell adhesion molecule 1 (NCAM1, also known as CD56) is a cell adhesion glycoprotein of the immunoglobulin (Ig) superfamily. It is a multifunction protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM1 is expressed on human neurons, glial cells, skeletal muscle cells, NK cells and a subset of T cells, and the expression is observed in a wide variety of human tumors, including myeloma, myeloid leukemia, neuroendocrine tumors, Wilms' tumor, neuroblastoma, and NK/T cell lymphomas. Three major isoforms of NCAM1, with molecular masses of 120, 140, and 180 kDa, are generated by alternative splicing of mRNA (PMID: 9696812). The glycosylphosphatidylinositol (GPI)-anchored NCAM120 and the transmembrane NCAM140 and NCAM180 consist of five Ig-like domains and two fibronection-type III repeats (FNIII). All three forms can be posttranslationally modified by addition of polysialic acid (PSA) (PMID: 14976519). Several other isofroms have also been described (PMID: 1856291).