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Nucleolin/C23 Polyklonaler Antikörper
Nucleolin/C23 Polyklonal Antikörper für
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
Konjugation
Cardinal Red™ Fluorescent Dye
Kat-Nr. : CR-10556
Synonyme
Geprüfte Anwendungen
Produktinformation
CR-10556 bindet in Nucleolin/C23 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | Nucleolin/C23 fusion protein Ag0859 |
| Vollständiger Name | nucleolin |
| Berechnetes Molekulargewicht | 76 kDa |
| Beobachtetes Molekulargewicht | 100-110 kDa |
| GenBank-Zugangsnummer | BC006494 |
| Gene symbol | NCL |
| Gene ID (NCBI) | 4691 |
| Konjugation | Cardinal Red™ Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 592 nm / 611 nm |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA |
| Lagerungsbedingungen | Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Nucleolin, also known as C23, involved in the control of transcription of ribosomal RNA (rRNA) genes by RNA polymerase I, in nucleocytoplasmic transportation of ribosomal components, and in ribosome maturation and assembly. It associated with intranucleolar chromatin and pre-ribosomal particles, and induced chromatin decondensation by binding to histione H1. Also it has a role in the process of transcriptional elongation. Whilst mammalian nucleolin has a predicted molecular mass of approximately 77 kDa, the apparent molecular mass is between 100 and 110 kDa, and has been attributed to the amino acid composition of the N-terminal domain, which is highly phosphorylated. (PMID: 15925566)
