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NDEL1 Monoklonaler Antikörper

NDEL1 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

1B3E9

Kat-Nr. : 68954-1-PBS

Synonyme

1B3E9, EOPA, MITAP1, Mitosin associated protein 1, Mitosin-associated protein 1

Filter:
  • Western Blot (WB) analysis of various lysates using NDEL1 Monoclonal antibody (68954-1-Ig)

    WB analysis using 68954-1-Ig (same clone as 68954-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68954-1-Ig (NDEL1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68954-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68954-1-PBS bindet in WB, ELISA NDEL1 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Maus, Ratte
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen NDEL1 fusion protein Ag11197
Vollständiger Name nudE nuclear distribution gene E homolog (A. nidulans)-like 1
Berechnetes Molekulargewicht 345 aa, 38 kDa, 41 kDa
Beobachtetes Molekulargewicht 38-42 kDa
GenBank-ZugangsnummerBC026101
Gene symbol NDEL1
Gene ID (NCBI) 81565
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Nuclear distribution factor E-homolog 1 (NDE1), NDE-like 1 (NDEL1), and Lissencephaly 1 (LIS1) together involve in essential neurodevelopmental processes, including neuronal precursor proliferation and differentiation, neurite outgrowth, and neuronal migration. All three bind directly to Disrupted in Schizophrenia 1 (DISC1), a scaffold protein critical to neuronal proliferation, integration, migration, and synaptic function within the developing and adult brain.[PMID: 18469341] Nuclear distribution element-like 1 (NDEL1) was firstly identified as a regulator of the cytoskeleton in microtubule and intermediate fliament dynamics and microtubule-based transport [PMID:21948775]. It is required for organization of the cellular microtubule array and microtubule anchoring at the centrosome, which is in part by targeting the microtubule severing protein KATNA1 to the centrosome[PMID:15728732].