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NDP Polyklonaler Antikörper

NDP Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 15380-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse testis tissue using NDP Polyclonal antibody (15380-1-AP)

    WB analysis of mouse testis using 15380-1-AP (same clone as 15380-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 15380-1-AP (NDP antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15380-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse eye tissue using NDP Polyclonal antibody (15380-1-AP)

    WB analysis of mouse eye using 15380-1-AP (same clone as 15380-1-PBS)

    mouse eye tissue were subjected to SDS PAGE followed by western blot with 15380-1-AP (NDP antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15380-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

15380-1-PBS bindet in WB, Indirect ELISA NDP und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen NDP fusion protein Ag4066
Vollständiger Name Norrie disease (pseudoglioma)
Berechnetes Molekulargewicht 15 kDa
Beobachtetes Molekulargewicht 50-60 kDa
GenBank-ZugangsnummerBC029901
Gene symbol NDP
Gene ID (NCBI) 4693
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NDP, also named as EVR2, ND and Norrin, is a secreted regulatory protein that remains tightly associated with the extracellular matrix. Mutations in the NDP gene are associated with the Norrie disease. Signaling induced by the protein NDP regulates vascular development of vertebrate retina and controls important blood vessels in the ear. It binds with high affinity to Frizzled 4, and Frizzled 4 knockout mice exhibit abnormal vascular development of the retina. This antibody detects 11-15 kDa (monomer) and 48 kDa (polymers, refer: 25692504).