NETO2 Rekombinanter Antikörper

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• KD/KO Validated

NETO2 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241451E10

Kat-Nr. : 84222-2-PBS

Synonyme

241451E10, Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2, BTCL2, NEOT2, Neuropilin and tolloid-like protein 2

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  WB analysis using 84222-2-RR (same clone as 84222-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84222-2-RR (NETO2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84222-2-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 84222-2-RR (same clone as 84222-2-PBS)

  WB result of NETO2 antibody (84222-2-RR; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-NETO2 transfected HEK-293 cells. This data was developed using the same antibody clone with 84222-2-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP01159-2

  Cytometric bead array standard curve of MP01159-2, NETO2 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84222-2-PBS. Detection antibody: 84222-4-PBS. Standard: Ag2971. Range: 0.156-20 ng/mL.

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  Affinity and Kinetic Characterization of 84222-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84222-2-RR against Human NETO2 were performed. The affinity constant is 0.203 nM.

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Geprüfte Anwendungen

Produktinformation

84222-2-PBS bindet in WB, Cytometric bead array, Indirect ELISA NETO2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: NETO2 fusion protein Ag2971
• Vollständiger Name: neuropilin (NRP) and tolloid (TLL)-like 2
• Berechnetes Molekulargewicht: 525 aa, 59 kDa
• Beobachtetes Molekulargewicht: 59 kDa
• GenBank-Zugangsnummer: BC012381
• Gene symbol: NETO2
• Gene ID (NCBI): 81831
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Neuropilin and tolloid-like 2 (NETO2), a member of the subfamily of CUB domain and LDLa-containing proteins, was identified as an auxiliary protein of neuronal kainate receptors (KARs) and played critical roles in regulating the functions of KARs. It was also able to bind to the active oligomeric form of K+-Cl− cotransporter (KCC2) to enhance its recycling in hippocampal neurons. Recently, elevated mRNA levels of NETO2 were detected in several types of tumors.