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NEURL4 Polyklonaler Antikörper

NEURL4 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55345-1-PBS

Synonyme

Neuralized-like protein 4, Neuralized like protein 4, KIAA1787

Filter:
  • Western Blot (WB) analysis of various lysates using NEURL4 Polyclonal antibody (55345-1-AP)

    WB analysis using 55345-1-AP (same clone as 55345-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 55345-1-AP (NEURL4 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55345-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55345-1-PBS bindet in WB, Indirect ELISA NEURL4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name neuralized homolog 4 (Drosophila)
Berechnetes Molekulargewicht 167 kDa
Beobachtetes Molekulargewicht 166 kDa
GenBank-ZugangsnummerNM_032442
Gene symbol NEURL4
Gene ID (NCBI) 84461
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NEURL4, also known as KIAA1787, has 6 highly conserved neuralized homology repeats (NHRs), which are thought to mediate protein-protein interactions. NEURL4 localizes to the daughter centriole and prevents formation of ectopic microtubule-organizing centers. NEURL4 promotes CCP110 ubiquitination and proteasome-dependent degradation, maintaining normal centrosomal homeostasis and preventing the formation of abnormal microtubule tissue centers (MTOCs) by countering CP110 accumulation(PMID: 22441691, 22261722).