NF-H/NF200 Monoklonaler Antikörper
NF-H/NF200 Monoklonal Antikörper für WB, IHC, IF-P, IF-Fro, FC (Intra), ELISA
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
Hausschwein, human, Maus, Ratte
Anwendung
WB, IHC, IF-P, IF-Fro, FC (Intra), ELISA
Konjugation
Unkonjugiert
CloneNo.
1A3C7
Kat-Nr. : 60331-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
60331-1-PBS bindet in WB, IHC, IF-P, IF-Fro, FC (Intra), ELISA NF-H/NF200 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten
Getestete Reaktivität | Hausschwein, human, Maus, Ratte |
Wirt / Isotyp | Maus / IgG2a |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | NF-H/NF200 fusion protein Ag13517 |
Vollständiger Name | neurofilament, heavy polypeptide |
Berechnetes Molekulargewicht | 112 kDa |
Beobachtetes Molekulargewicht | 200 kDa |
GenBank-Zugangsnummer | BC014185 |
Gene symbol | NF-H |
Gene ID (NCBI) | 4744 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
NEFH, also named as KIAA0845 and NFH, Belongs to the intermediate filament family. It has an important function in mature axons that is not subserved by the two smaller NF proteins. Neurofilaments are the 10nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton, and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE: NF-L, 65-68 kDa; NF-M,145-160 kDa and NF-H, 200-220 kDa. This antibody recognize NEFH only.