NF-H/NF200 Monoklonaler Antikörper

NF-H/NF200 Monoklonal Antikörper für WB, IHC, IF-P, IF-Fro, FC (Intra), ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, IHC, IF-P, IF-Fro, FC (Intra), ELISA

Konjugation

Unkonjugiert

CloneNo.

1A3C7

Kat-Nr. : 60331-1-PBS

Synonyme

NEFH, Neurofilament heavy polypeptide, NF200, NF-H, 1A3C7



Geprüfte Anwendungen

Produktinformation

60331-1-PBS bindet in WB, IHC, IF-P, IF-Fro, FC (Intra), ELISA NF-H/NF200 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

Getestete Reaktivität Hausschwein, human, Maus, Ratte
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen NF-H/NF200 fusion protein Ag13517
Vollständiger Name neurofilament, heavy polypeptide
Berechnetes Molekulargewicht 112 kDa
Beobachtetes Molekulargewicht 200 kDa
GenBank-ZugangsnummerBC014185
Gene symbol NF-H
Gene ID (NCBI) 4744
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NEFH, also named as KIAA0845 and NFH, Belongs to the intermediate filament family. It has an important function in mature axons that is not subserved by the two smaller NF proteins. Neurofilaments are the 10nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton, and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE: NF-L, 65-68 kDa; NF-M,145-160 kDa and NF-H, 200-220 kDa. This antibody recognize NEFH only.