NGFR/TNFRSF16 Rekombinanter Antikörper

NGFR/TNFRSF16 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242634B10

Kat-Nr. : 98391-2-PBS

Synonyme

CD271, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, Low-affinity nerve growth factor receptor p75NGFR, Low-affinity nerve growth factor receptor p75NGR

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  FC experiment of Transfected HEK-293T using 98391-2-RR (same clone as 98391-2-PBS)

  1x10^6 HEK-293T cells or Ngfr transfected HEK-293T cells were stained with 0.25 ug Anti-Mouse NGFR/TNFRSF16 Rabbit RecAb (98391-2-RR, Clone:242634B10) and PE-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98391-2-PBS in a different storage buffer formulation.

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  FC experiment of Transfected HEK-293T using 98391-2-RR (same clone as 98391-2-PBS)

  1x10^6 HEK-293T cells(left) or Ngfr transfected HEK-293T cells(right) were stained with 0.25 ug Anti-Mouse NGFR/TNFRSF16 Rabbit RecAb (98391-2-RR, Clone:242634B10) (red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L).Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98391-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98391-2-PBS bindet in FC NGFR/TNFRSF16 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: nerve growth factor receptor (TNFR superfamily, member 16)
• Berechnetes Molekulargewicht: 46 kDa
• GenBank-Zugangsnummer: NM_033217.3
• Gene symbol: Ngfr
• Gene ID (NCBI): 18053
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

The nerve growth factor (NGF) receptor (NGFR), also known as p75NTR, TNFRSF16, belongs to the tumor necrosis factor receptor superfamily, which is a low-affinity receptor of neurotrophins including NGF,1 brain-derived neurotrophic factor (BDNF),2 and neurotrophin-3, -4, and -5.It is now apparent that expression of NGFR is ubiquitous and not limited to the nervous system, being expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells and myoepithelial cells (PMID: 38307025, 16424897).