NHE1 Monoklonaler Antikörper

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• KD/KO Validated

NHE1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3D9F3

Kat-Nr. : 67363-1-PBS

Synonyme

SLC9A1, 3D9F3, APNH, APNH1, FLJ42224

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  WB analysis using 67363-1-Ig (same clone as 67363-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67363-1-Ig (NHE1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Lamin B1 Monoclonal antibody (HRP-66095) as loading control. This data was developed using the same antibody clone with 67363-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

67363-1-PBS bindet in WB, Indirect ELISA NHE1 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: NHE1 fusion protein Ag14329
• Vollständiger Name: solute carrier family 9 (sodium/hydrogen exchanger), member 1
• Berechnetes Molekulargewicht: 815 aa, 91 kDa
• Beobachtetes Molekulargewicht: 110 kDa
• GenBank-Zugangsnummer: BC012121
• Gene symbol: NHE1
• Gene ID (NCBI): 6548
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NHE1, also named as SLC9A1, is involved in pH regulation that can eliminate acids generated by active metabolism and counter adverse environmental conditions. NHE1 plays an important role in signal transduction. It has been shown that NHE1 participates in the development and progression of human breast cancer, gastric cancer and others. NHE1 has some isoforms with 91 kDa , 110 kDa (phosphoglycoprotein) and 210 kDa (dimeric protein). (PMID:28098891, 27751915, 8300588)