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NHE2 Polyklonaler Antikörper

NHE2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25105-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using NHE2 Polyclonal antibody (25105-1-AP)

    WB analysis using 25105-1-AP (same clone as 25105-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25105-1-AP (NHE2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25105-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25105-1-PBS bindet in WB, Indirect ELISA NHE2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen NHE2 fusion protein Ag18801
Vollständiger Name solute carrier family 9 (sodium/hydrogen exchanger), member 2
Berechnetes Molekulargewicht 812 aa, 92 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerBC136377
Gene symbol NHE2/SLC9A2
Gene ID (NCBI) 6549
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NHE2, also known as SLC9A2, is a protein-coding gene mainly at the top of gastrointestinal epithelial cells. It mainly encodes a member of the sodium-hydrogen exchanger (NHE) protein family, which is localized to the apical membrane and is easily degraded by lysosomes, resulting in a short half-life. NHE2 is involved in sodium ion transport by exchanging intracellular hydrogen ions into external sodium ions, and helps in the regulation of cell pH and volume to eliminate acids produced by active metabolism or against adverse environmental conditions. NHE2 is widely distributed in tissues of the gastrointestinal tract, kidney, heart, testes, uterus, and adrenal glands (PMID: 37688782). The observed molecular weight of NHE2 is 70 kDa, which might be the unmodified form of NHE2 (PMID: 10444453, 10666043).